Morphological evidence of cyclic changes observed in Leydig cells of a chimeric mouse.

Light and electron microscopy were employed in studying morphologic heterogeneity in Leydig cells (LC) in situ, as manifested in a chimeric mouse. This mouse was chosen to take advantage of increased LC concentration in territories of agametic tubules (Hrudka et al., 1989).

Co-existence of gametic and agametic seminiferous tubules in a chimeric mouse. A light- and electron-microscopic study.

Six chimeras, including 4 phenotypic males and 2 females, were produced by aggregation of F1 (C57BL x BALB/c) and Swiss white embryos. All were fertile, except 1 male, whose deviation in testicular structure prompted this light- and electron-microscopic study. This chimera had a well-developed sperm-conducting system, sperm in the epididymis and active accessory sex glands.