Publications by authors named "W K Clarkston"

Immune checkpoint inhibitors commonly cause gastrointestinal immune-related adverse effects. These patients also carry an increased risk of concomitant infections. This 66-year-old man with immune checkpoint inhibitor colitis was discovered to have concurrent and colitis.

View Article and Find Full Text PDF

Limited objective data exist on the comparison of post-endoscopic retrograde cholangiopancreatography (ERCP) complications in patients with cirrhosis based on the severity of the disease. We evaluated the effectiveness of the Child-Turcotte-Pugh (CTP) score system in anticipating the risk of post-ERCP complications in patients with cirrhosis. The PubMed, Scopus, Embase, and Cochrane databases were searched from inception through September 2022 to identify studies comparing post-ERCP complications in patients with cirrhosis based on CTP score.

View Article and Find Full Text PDF
Article Synopsis
  • Gastrointestinal bleeding (GIB) is frequent in patients with left ventricular assist devices (LVADs), but the best screening method before implantation is not well defined.
  • A study at Saint Luke's Hospital analyzed data from 167 LVAD patients, revealing that pre-implantation endoscopic evaluations showed a high occurrence of angiodysplasia but did not reduce overall GIB rates.
  • The findings support avoiding routine pre-LVAD endoscopic screening, advocating for individualized assessments based on each patient’s circumstances instead.
View Article and Find Full Text PDF
Article Synopsis
  • - The study compared the adequacy of tissue samples for molecular testing in pancreatic cancer obtained through endoscopic ultrasound (EUS) fine-needle aspiration (FNA) and fine-needle biopsy (FNB) methods at Saint Luke's Hospital from 2018 to 2021.
  • - Out of 132 patients, FNB samples were significantly more adequate for molecular (71.4%) and genomic testing (46.4%) compared to FNA samples (32.1% and 23.8%, respectively).
  • - The number of passes needed for effective diagnosis was similar for both methods, but FNB proved to be more effective overall for achieving suitable samples for molecular testing, highlighting the importance of tumor surface area and cellular
View Article and Find Full Text PDF

CRC accounts for approximately a tenth of all cancer cases and deaths in the US. Due to large differences in demographics among the different states, we aim to determine trends in the CRC epidemiology and across different states, age groups, and genders. CRC rates, age-adjusted to the standard US population, were obtained from the GBD 2019 database.

View Article and Find Full Text PDF