Amphiphilic paramagnetic neutral gold dithiolene complexes.

The sulfiding of benzils with P(4)S(10) in 1,3-dimethyl-2-imidazolidinone (DMI) as solvent allows for a direct synthesis of neutral radical, gold dithiolene complexes based on 1,2-bis-(4-alkoxy-phenyl)ethylene-1,2-dithiolate ligands with n-butyl, n-octyl and n-dodecyl chains. The three neutral and soluble complexes Au-OC(4), Au-OC(8) and Au-OC(12) exhibit a near infrared (NIR) absorption band around 1.5 mum and EPR characteristics which confirm a strong delocalization of the spin density on the electron-rich dithiolene ligands.

Polyamines and pyrimidines in blood plasma and urine of dogs bearing mammary tumours.

The blood plasma and urinary pattern of polyamines and pyrimidines in dogs bearing mammary tumours was examined. A large variability of pyrimidines in blood plasma and spermidine, spermine and pseudouridine in urine of healthy and tumour-bearing dogs was observed. The blood plasma level of uracil and uridine as well as urinary concentration of pseudouridine and spermidine/spermine ratio were significantly elevated in dogs with mammary tumours.