A Health Risk Assessment of Workers Exposed to Organic Paint Solvents Used in the Korean Shipbuilding Industry.

In the shipbuilding industry, during the painting process, workers are exposed to various substances in paint, including organic solvents that can adversely affect their health. Most workplace exposures to organic solvents involve mixtures of organic compounds. Therefore, in this study, the hazard quotient (HQ) and hazard index (HI) were derived using data from the Workplace Environmental Monitoring Program in Korea for six organic solvents (xylene, n-butanol, ethylbenzene, isobutyl alcohol, toluene, and methylisobutyl ketone [MIBK]) commonly used in the steel shipbuilding industry.

Bioactivity Evaluation and Phytochemical Characterization of (Thunb.) Siebold Leaf Extract.

Background: () has traditionally been used for medicinal purposes, and its leaves are considered edible. While is known for its diverse biological activities, the antioxidant, antidiabetic, and anticancer effects of its leaves extracted using different solvents have not been thoroughly investigated.

Methods: This study examined the antioxidant, antidiabetic, anticancer, and life-prolonging effects of () leaf extract.

Systematic Review-Based Treatment Algorithm for the Multidisciplinary Treatment of Lung Cancer Bone Metastases.

The prognosis for patients with lung cancer bone metastases has improved with the use of novel systemic agents. These patients might need surgery or radiotherapy to alleviate symptoms or maintain function. However, there is currently no disease specific algorithm to guide multidisciplinary decisions.

3-Bromo-4,5-dihydroxybenzaldehyde Attenuates Allergic Contact Dermatitis by Generating CD4Foxp3 T cells.

Background/aim: Regulatory T cells (Tregs) play a crucial role in inflammatory responses by regulating the activity of various immune cells. M2 macrophages induced by IL-10 and TGF-β exhibit anti-inflammatory functions and induce Treg differentiation. Although the beneficial effects of 3-bromo-4,5-dihydroxybenzaldehyde (BDB) on various diseases have been widely reported, the mechanisms, through which it alleviates allergic contact dermatitis (ACD) via Tregs and macrophages, are not well understood.

Soybean mitogen-activated protein kinase GmMPK6 enhances drought tolerance.

Soybeans are a critical crop that provides both protein and oil. In response to environmental stresses, mitogen-activated protein kinases (MPKs) play a key role in transmitting stress signals to the nucleus to initiate stress-responsive actions. Drought stress reduces plant development and productivity but the specific MPK responsible for drought stress responses has not been previously identified.