Publications by authors named "W J van Rooij"

Background: In addition to the elimination diet, dietary composition may influence disease severity in patients with eosinophilic esophagitis (EoE) through modulation of the immune response.

Aim: To explore the immunomodulatory role of nutrition before and during elimination diet in adult EoE patients.

Methods: Nutritional intake was assessed in 39 Dutch adult EoE patients participating in the Supplemental Elemental Trial (Dutch trial registry NL6014, NTR6778) using 3-day food diaries.

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Article Synopsis
  • Eosinophilic esophagitis (EoE) is a chronic inflammatory condition affecting the esophagus, which typically requires invasive procedures for monitoring tissue changes and treatment response.
  • This study aimed to explore whether specific proteins in the serum could serve as non-invasive biomarkers to reflect tissue remodeling and clinical outcomes in adults with EoE.
  • Results indicated that certain collagen fragments and other extracellular matrix proteins in the serum correlated with disease severity and treatment responses, suggesting their potential utility in monitoring EoE progression and therapy effectiveness.
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Background: Radiotherapy (RT) is involved in about 50% of all cancer patients, making it a very important treatment modality. The most common type of RT is external beam RT, which consists of delivering the radiation to the tumor from outside the body. One novel treatment delivery method is volumetric modulated arc therapy (VMAT), where the gantry continuously rotates around the patient during the radiation delivery.

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Background: Clinical data used to train deep learning models are often not clean data. They can contain imperfections in both the imaging data and the corresponding segmentations.

Purpose: This study investigates the influence of data imperfections on the performance of deep learning models for parotid gland segmentation.

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