Prediction of biochemical recurrence after radical prostatectomy from primary tumour characteristics.

Objectives: To construct and externally calibrate a predictive model for early biochemical recurrence (BCR) after radical prostatectomy (RP) incorporating clinical and modern imaging characteristics of the primary tumour.

Patients And Methods: Patients who underwent RP following multiparametric magnetic resonance imaging, prostate biopsy and prostate-specific membrane antigen-positron emission tomography/computed tomography (PSMA-PET/CT), from two centres in Australia and the Netherlands. The primary outcome was biochemical recurrence-free survival (BRFS), where BCR was defined as a rising PSA level of ≥0.

Clinicopathologic Significance of Anterior Prostate Cancer: Comparison With Posterior Prostate Cancer in the Era of Multiparametric Magnetic Resonance Imaging.

Anterior prostate cancer (APC) has been considered an indolent tumor, most commonly arising in the transition zone (TZ). More recently, detection of APC has been facilitated through multiparametric magnetic resonance imaging and improved biopsy techniques, enabling earlier detection. The pathologic features and clinical significance of pure APC in a large contemporary series of well-characterized tumors have, to date, not been elucidated.

Obstructive uropathy - acute and chronic medical management.

Obstructive uropathy is an important cause of acute and chronic kidney disease. Decompression of the urinary tract is an essential aspect of treatment. The cause and aetiology of obstruction typically determine the surgical approach.

Penile strangulation due to metallic foreign body; A rare case report highlighting effective management strategies for clinicians.

Penile strangulation from a foreign body is a time critical and rare presentation to the emergency department. The rarity of the presentation leads to its management being haphazard by the treating clinicians leading to suboptimal outcomes. We present a 44-year-old male with nine metal rings strangulating his penis and scrotum who failed multiple attempts by the department to free the penis and required an industrial circular saw provided by the fire-brigade to successfully cut the rings.

Corrigendum: Correction of the Abstract. Focal therapy for prostate cancer with irreversible electroporation: Oncological and functional results of a single institution study.

This corrects the article on p. 285 in vol. 63, PMID: 35534217.