Fluorescent in situ hybridization has been the definitive modality in testing for overexpression of the Human Epidermal Growth Factor Receptor 2 (HER2) for decades to guide the appropriate treatment for cancer patients. In more recent years innovation and new techniques have been developed to supplant or even replace FISH as a standard method for biomarker testing. Alternative testing methods such polymerase chain reaction (PCR), next-generation sequencing (NGS), and other in situ hybridization (ISH)-derived techniques such as chromogenic-ISH (CISH) have been shown in multiple publications to have high concordance with FISH in addition to advantages in economics, logistics and practicality to the point where CISH and derived methods appear to have eclipsed FISH as a testing method of choice after immunohistochemistry (IHC).
View Article and Find Full Text PDFThe purpose of the current research effort was two-fold: (a) determine what behaviors successful veteran job candidates perform during the job application process that distinguish them from less successful ones, and (b) identify the behaviors of successfully employed veterans that distinguish them from those that are less successful or unable to maintain civilian employment. To address these issues, a research initiative was undertaken by the City of Clarksville, TN; Montgomery County, TN; the Tennessee Department of Labor; and the Tennessee Department of Veterans Services. Researchers conducted a qualitative study in the environs of Nashville, TN and Clarksville, TN, where Fort Campbell a United States Army installation, is located.
View Article and Find Full Text PDFThe primary goal of this investigation is to determine the feasibility of using vibrational spectroscopy techniques for the analysis of soil samples in order to characterize a specific area and hence create a soil map for use in forensic investigation. We compare spectra of "artifacts" which are exclusive to a single location or area rather than focus on the general intrinsic components of soil. Comparison of these artifacts may allow the creation of a map of different regions and thus allow matching of soil evidence to these regions (spectra).
View Article and Find Full Text PDFJ Evid Inf Soc Work
September 2018
Objective: Sex trafficking is an unrelenting problem in Mississippi. No quantitative data currently exist on the prevalence of sex trafficking or the identification of victims in the state.
Method: This study used the Trafficking in Victims Identification Tool (TVIT) (Short Version) to identify the extent to which a sample of clients (n = 28) receiving services at a non-profit social services agency in Jackson, Mississippi, were also victims of sex trafficking.