Publications by authors named "W J Ravich"

The author offers his approach to esophageal dilation based on 40 years of a practice specializing in swallowing disorders and esophageal disease. He discusses general concepts in the management of esophageal strictures and then provides an approach to dilation of different types of esophageal stenotic lesions.

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Purpose Of Review: This paper presents the author's approach to esophageal dilation. It offers a tailored approach to the application of dilation to specific types of esophageal stenotic lesions.

Recent Findings: In patients with inflammatory stricture, recent studies confirm the importance of treating the underlying inflammatory condition in order to decrease the rate of recurrence.

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Article Synopsis
  • The study evaluated the safety and effectiveness of upper esophageal sphincter (UES) dilatation for treating cricopharyngeal (CP) dysfunction and analyzed various factors related to symptom improvement.
  • A total of 31 patients were assessed, with a median age of 63, primarily suffering from dysphagia, and 79% reported symptomatic improvement after the procedure.
  • Both retrograde and static dilatation techniques were used, showing similar rates of symptom improvement, indicating that the dilatation method may not significantly affect outcomes.
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Eosinophilic esophagitis (EoE) is a chronic, immune-mediated disease resulting in symptoms of esophageal dysmotility. Abnormalities include dysphagia, food impaction and reflux. Although men appear to comprise a majority of the EoE population, few studies have directly assessed gender-associated clinical differences.

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Objectives: Long non-coding RNAs (lncRNA) have been shown to play important roles in the development and progression of cancer. However, functional lncRNAs and their downstream mechanisms are largely unknown in the molecular pathogenesis of oesophageal adenocarcinoma (EAC) and its progression.

Design: lncRNAs that are abnormally upregulated in EACs were identified by RNA-sequencing analysis, followed by quantitative RT-PCR (qRTPCR) validation using tissues from 25 EAC patients.

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