Gene expression of calcium transporters Calbindin-D28K and TRPV6 in Japanese quails (Coturnix japonica) subjected to phytase super-dosing and under different temperatures.

This study aimed to evaluate the effects of phytase super-dosing in the diet of laying quails subjected to different temperatures, their performance, blood biochemistry, and gene expression of the epithelial calcium transporters Calbindin-D28 K and TRPV6. Seven hundred and twenty (720) Japanese quails in the production phase were distributed in a completely randomized design, in a 5 × 3 factorial scheme, with five levels of phytase supplementation (0, 500, 1000, 1500 and 3000 FTU/kg) and three temperatures (24°C, 30°C and 36°C), totaling 15 treatments, and six replicates of eight birds each. The study began at 8 weeks of age and continued for two 21-day cycles, totaling 42 days of experiment.

Exploring Quinoline Derivatives: Their Antimalarial Efficacy and Structural Features.

Objectives: Malaria continues to be the primary cause of mortality worldwide, and timely recognition and prompt intervention are crucial in mitigating adverse consequences. This review article aims to examine the effectiveness and structural characteristics of quinoline-based compounds as antimalarial agents. It specifically focuses on their therapeutic effects as well as potential prospects for exploring structure-activity relationship (SAR).

Remote team-based learning during COVID-19: lower academic performance is associated with the exclusion of test grades from final grades.

Background: Magdalon et al. demonstrated that excluding iRAT grades from the final grade calculation of the course negatively impacted student performance and attendance in team-based learning sessions.

Introduction: The COVID-19 pandemic necessitated a shift from in-person to remote learning, including team-based learning activities.

Predictors of Salmonella enterica contamination in agricultural and livestock-impacted natural watersheds.

Salmonella enterica (S. enterica), a ubiquitous zoonotic foodborne pathogen, remains a worldwide public health hazard and economic burden. In recent years, outbreaks associated with the consumption of plant-based foods probably contaminated by irrigation water highlights the importance of water sources.

Environmental and human health risk assessment of potentially toxic elements in rehabilitating iron mine lands in the Brazilian Amazon.

Waste pile substrates from Fe mining may carry potentially toxic elements (PTE). Rehabilitation efforts must maintain soil vegetation cover effectively, avoiding the dispersion of particulate matter and reducing the risk to the environment and human health. Therefore, this study aims to evaluate the pseudo-total and extractable contents, perform chemical fractionation, and assess the bioaccessibility and risk of PTE in waste piles of Fe mining in the Eastern Amazon.