MADVent: A low-cost ventilator for patients with COVID-19.

The COVID-19 pandemic has produced critical shortages of ventilators worldwide. There is an unmet need for rapidly deployable, emergency-use ventilators with sufficient functionality to manage COVID-19 patients with severe acute respiratory distress syndrome. Here, we show the development and validation of a simple, portable and low-cost ventilator that may be rapidly manufactured with minimal susceptibility to supply chain disruptions.

Usefulness of the Duke Sudden Cardiac Death risk score for predicting sudden cardiac death in patients with angiographic (>75% narrowing) coronary artery disease.

The currently available sudden cardiac death (SCD) risk prediction tools fail to identify most at-risk patients and cannot delineate a specific patient's SCD risk. We sought to develop a tool to improve the risk stratification of patients with coronary artery disease. Clinical, demographic, and angiographic characteristics were evaluated among 37,258 patients who had undergone coronary angiography from January 1, 1985 to May 31, 2005, and who were found to have at least one native coronary artery stenosis of > or =75%.

Anesthesia-controlled time and turnover time for ambulatory upper extremity surgery performed with regional versus general anesthesia.

Study Objective: To test the hypothesis that regional anesthesia (RA) employing a block room reduces anesthesia-controlled time for ambulatory upper extremity surgery compared with general anesthesia (GA).

Design: Retrospective cohort study.

Setting: Outpatient surgery center of a university hospital.

Differences in day and night shift clinical performance in anesthesiology.

Objective: This study examined whether anesthesia residents (physicians in training) performed clinical duties in the operating room differently during the day versus at night.

Background: Fatigue from sleep deprivation and working through the night is common for physicians, particularly during residency training.

Methods: Using a repeated-measures design, we studied 13 pairs of day-night matched anesthesia cases.