Publications by authors named "W J Bowers"
Article Synopsis
- - Dedifferentiated liposarcoma (DDL) is a rare and aggressive subtype typically found in the retroperitoneum, with challenging diagnostics, especially when it occurs in the mesentery as documented in very few cases.
- - A 76-year-old woman was discovered to have a large mesenteric mass incidentally while being treated for pneumonia, leading to surgery where a tumor adherent to the intestine was removed and identified as intermediate-grade DDL.
- - The case emphasizes the need to include mesenteric DDL in the differential diagnosis of large abdominal masses, highlighting that complete surgical resection is crucial for treatment, alongside regular follow-ups due to its aggressive nature.
Article Synopsis
- Internal hernias are a rare but serious cause of bowel obstruction, which can lead to high rates of morbidity and mortality if not quickly identified and treated.
- A case study of a 75-year-old woman shows the challenges of diagnosing a transverse mesocolic internal hernia after a Hartmann reversal procedure, as her symptoms were initially mistaken for postoperative ileus.
- Successful surgical intervention was performed after a delayed diagnosis, highlighting the need for healthcare providers to consider internal hernias when diagnosing small bowel obstructions, particularly in patients with prior abdominal surgeries.
Spontaneous or atraumatic splenic rupture (ASR) is a rare but life-threatening condition that requires swift recognition and intervention. We report the case of a 66-year-old female with a history of hypothyroidism, appendiceal goblet cell adenocarcinoma, and new-onset atrial fibrillation (Afib) requiring anticoagulation. She initially presented with right upper quadrant abdominal pain.
View Article and Find Full Text PDFColonic xanthomas are a rare finding, particularly when combined with a tubular adenoma in a single polyp. While transformation to malignancy is not thought to be higher than that of a tubular adenoma alone, there is still concern as to the pathophysiology of xanthoma formation within the colon and what that may mean for patient outcomes. Here, we present a patient undergoing a routine screening colonoscopy with the removal of a rectosigmoid polyp consistent with xanthoma and tubular adenoma histopathology.
View Article and Find Full Text PDFHomology between mitochondrial DNA (mtDNA) and nuclear DNA of mitochondrial origin (nuMTs) causes confounding when aligning short sequence reads to the reference human genome, as the true sequence origin cannot be determined. Using a systematic approach, we here report the impact of all potential mitochondrial variants on alignment accuracy and variant calling. A total of 49,707 possible mutations were introduced across the 16,569 bp reference mitochondrial genome (16,569 × 3 alternative alleles), one variant at-at-time.
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