Publications by authors named "W J Becker"
Importance: Chronic pain is common among individuals with dialysis-dependent kidney failure.
Objective: To evaluate the effectiveness of pain coping skills training (PCST), a cognitive behavioral intervention, on pain interference.
Design, Setting, And Participants: This multicenter randomized clinical trial of PCST vs usual care was conducted across 16 academic centers and 103 outpatient dialysis facilities in the US.
Objective: Neurocognitive symptoms (NCS) may be early indicators of opioid-related harm. We aimed to evaluate the incidence and potential attribution of opioid-related NCS among patients on long-term opioid therapy (LTOT) by using natural language processing (NLP) to extract data from the electronic health records (EHR) within the Veterans Health Administration.
Methods: We conducted a retrospective cohort study of patients prescribed LTOT in 2018.
Objectives: With over 184,000 new cases and more than 99,000 deaths per year, malignancies of the larynx are a global health problem. Currently, a dedicated screening method enabling a direct onsite diagnosis is missing. This can lead to delayed diagnosis and worse outcomes of the patients.
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- Patients on long-term opioid therapy for chronic pain often still suffer from unrelieved pain and quality of life issues.
- This study compared two approaches for managing these patients: an integrated pain team (IPT) focused on holistic care versus pharmacist collaborative management (PCM) concentrated on medication optimization.
- Results showed similar outcomes for both groups in terms of pain response and opioid dosage reduction after 12 months, indicating that both methods can be effective in managing chronic pain.
Various public health measures have contained outbreaks of SARS-CoV-2, but concerns remain over the possibility of future surges. Improvements in broadening the vaccine response can stifle new and nascent infections. In this study, we tested the effects of different adjuvant combinations on the immunization of mice with the receptor-binding domain (RBD)-containing the S1-subunit of the spike protein (S1 protein) from SARS-CoV-2 to induce a robust humoral and cellular immune response.
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