First-trimester euploid miscarriages analysed by array-CGH.

It is estimated that 10-15 % of all clinically recognised pregnancies results in a miscarriage, most of which occur during the first trimester. Large-scale chromosomal abnormalities have been found in up to 50 % of first-trimester spontaneous abortions and, for several decades, standard cytogenetic analysis has been used for their identification. Recent studies have proven that array comparative genomic hybridisation (array-CGH) is a useful tool for the detection of genome imbalances in miscarriages, showing a higher resolution, a significantly higher detection rate and overcoming problems of culture failures, maternal contamination and poor chromosome morphology.

[Intestinal intussusception in pregnancy with obstruction, caused by benign neurilemmoma. Role of abdominal echocardiography in the preoperative diagnosis].

A rare case of intestinalm obstruction caused by intussusception of the small bowel due to an intraparietal benign neurilemmoma (synonym: benign schwannoma) in a patient 35th weeks pregnant is reported. It is assumed that intestinal intussusception during pregnancy is a rare complication and the diagnosis is made difficult due to the pregnancy itself, delaying the onset of symptoms and treatment. The echography was the determining factor for the diagnosis.