Publications by authors named "W Hoch"
Introduction: Skin and soft tissue infections (SSTIs) present with variable severity. The American Association for the Surgery of Trauma (AAST) developed an emergency general surgery (EGS) grading system for several diseases. We aimed to determine whether the AAST EGS grade corresponds with key clinical outcomes.
View Article and Find Full Text PDFThe dwindling repertoire of antibiotics to treat methicillin-resistant Staphylococcus aureus (MRSA) calls for novel treatment options. Quorum-quenching agents offer an alternative or an adjuvant to antibiotic therapy. Three biaryl hydroxyketone compounds discovered previously (F1, F12, and F19; G.
View Article and Find Full Text PDFBackground: Visitors may play a significant role in patient care by interceding on patients' behalf and advocating proper care.
Study Objectives: The objectives of this study were to determine the percentage of emergency department (ED) patients with visitors, whether this varied by gender or race, and to compare patient and visitor perspectives on the role and importance of visitors.
Methods: This cross-sectional study was done in a 46,035 adult-visit, urban ED during a consecutive 96-h period.
Article Synopsis
- MuSK is a critical receptor for forming and maintaining nerve-muscle synapses, with associated proteins playing key roles in this process.
- Although synaptic development in biglycan-deficient mice appears normal at first, abnormalities in synapse structure and stability emerge by 5 weeks post-birth.
- Biglycan interacts with MuSK and is essential for the stability of acetylcholine receptor clusters, suggesting it acts as a vital ligand for MuSK at neuromuscular junctions.