Publications by authors named "W Habre"
Article Synopsis
- Intestinal ischemia-reperfusion injury can lead to both large-scale (macrocirculatory) and small-scale (microcirculatory) blood flow failures, and the study aimed to test if combining a vasoconstrictor (norepinephrine) with a vasodilator (ilomedin) improves blood pressure and circulation after injury.
- The research was conducted on 21 pigs, with three groups receiving different treatments before and after a 2-hour induced small bowel ischemia followed by reperfusion, measuring various circulatory parameters and biomarkers.
- Results showed no significant differences in mean arterial pressure or cardiac index between the groups, but the combination therapy group had notably better microcirculation performance immediately after and two
The score for prediction of postoperative respiratory complications in infants and children (SPORC-C) was recently reported. The score was developed using a large cohort of patients by applying a multivariate model, then internally and externally validated on a different cohort of patients. In order to encourage use of this score, an online calculator (https://sites.
View Article and Find Full Text PDFLessons learned from big data (APRICOT, NECTARINE, PeDI).
Best Pract Res Clin Anaesthesiol
June 2024
Big data in paediatric anaesthesia allows the evaluation of morbidity and mortality of anaesthesia in a large population, but also the identification of rare critical events and of their causes. This is a major step to focus education and design clinical guidelines. Moreover, they can help trying to determine normative data in a population with a wide range of ages and body weights.
View Article and Find Full Text PDFBackground: Introducing variability in tidal volume, ventilatory frequency, or both is beneficial during mechanical ventilation in acute respiratory distress syndrome (ARDS). We investigated whether applying cycle-by-cycle variability in the positive end-expiratory pressure (PEEP) exerts beneficial effect on lung function in a model of ARDS.
Methods: Rabbits with lung injury were randomly allocated to receive mechanical ventilation for 6 h by applying a pressure-controlled mode with constant PEEP of 7 cm HO (PC group: =6) or variable PEEP (VEEP) with a coefficient of variation of 21.