Publications by authors named "W H Oddy"
Background: Multiple sclerosis is characterised by acute and chronic inflammation in the CNS. Diet may influence inflammation, and therefore MS outcomes.
Objective: To determine whether the Dietary Inflammatory Index (DII) is associated with depression, anxiety, and fatigue in a prospective cohort of people with MS.
Objective: To determine whether the dietary inflammatory index (DII) scores were associated with knee structural changes and pain over a 10.7-year follow-up.
Methods: This study used data from a prospective population-based cohort study (mean age 63 years, 51% female) in which 1,099, 875, 768, and 566 participants completed assessments at baseline, 2.
Article Synopsis
- - The study investigates how the DASH diet score influences systolic blood pressure (BP) in relation to genetic factors, analyzing data from over 127,000 participants from different population groups, primarily European.
- - Researchers identified several genetic loci associated with interactions between an individual's genetics and their response to the DASH diet, particularly focusing on the variant rs117878928 at chromosomal location 15q25.1.
- - Results suggest significant gene-DASH diet interactions affecting systolic BP, highlighting the need for further research in larger, more diverse populations to confirm these findings.
Purpose Of Review: Falls are a major global public health issue and the second cause of unintentional injury death. Nutrition may be an important factor for falls prevention in adults, but most previous studies examined the associations between single nutrients and falls. The use of dietary patterns is an alternative method to measure whole diet and its relationship with health outcomes.
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- The study investigated how genetic variations (genotype) interact with dietary habits (specifically the DASH diet score) to influence systolic blood pressure (SBP).
- Researchers analyzed a massive dataset of genetic information from over 127,000 individuals to identify specific genetic locations (loci) that may play a role in this interaction.
- They found significant genetic interactions with the DASH diet score, especially at a specific gene location (rs117878928), indicating that diet can affect blood pressure differently based on an individual's genetic makeup, which highlights the need for further research with more diverse populations.