Publications by authors named "W H OTTO"
Background: Comparative studies of outcomes between different biological mitral valve prostheses are scarce. This study compares the late clinical results of valve replacement with the Epic and Mosaic bioprostheses.
Methods: Patients undergoing isolated elective mitral valve replacement (MVR) between 2005 and 2019 were eligible for inclusion.
Objective: This study compares early and long-term outcomes following mitral valve (MV) repair and replacement in patients with mitral regurgitation (MR) and reduced left ventricular ejection fraction (LVEF).
Methods: Patients with primary or secondary MR and LVEF <50% who underwent MV replacement or repair (with/without atrial septal defect closure and/or atrial fibrillation ablation) between 2005 and 2017 at our center were retrospectively analyzed using unadjusted and propensity score matching techniques (42 pairs).
Results: A total of 356 patients with either primary (n = 162 [45.
Background: Respiratory infections cause a significant amount of morbidity and mortality in pediatric and young adult patients with malignancy. Bronchoscopy with bronchoalveolar lavage (BAL) is frequently utilized in the diagnostic process, but which patients would most benefit is poorly understood.
Methods: A retrospective study from 2013 to 2022 examined patients with active malignancy who underwent bronchoscopy with BAL.
Influenza is a major cause of morbidity and mortality for pediatric cancer patients. We review important aspects in the management of influenza, including virology, epidemiology, clinical presentation, diagnostic testing, and antiviral treatment. Topics that are addressed include optimal treatment of influenza in children with cancer as well as strategies for prevention.
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- The German Federal Institute for Medicines and Medical Products has restricted fosfomycin use in transrectal biopsy of the prostate (TRBP), highlighting the urgent need for alternative antibiotic prophylaxis options.
- A study involving 359 patients at the University of Regensburg found that using amoxicillin/clavulanic acid resulted in a low post-TRBP infection hospitalization rate of only 2.8%, suggesting its effectiveness as an alternative.
- Amoxicillin/clavulanic acid is classified as an "Access" antibiotic by the WHO, making it a preferable choice; however, the study's limitations include not conducting rectal swabs and urine cultures for every patient.