Myelitis associated with glial fibrillary acidic protein IgG: characterization and comparison with aquaporin-4 IgG and myelin oligodendrocyte glycoprotein IgG myelitis.

Background: Awareness of the characteristics of glial fibrillary acidic protein autoantibody (GFAP-IgG) associated myelitis facilitates early diagnosis and treatment. We explored features in GFAP-IgG myelitis and compared them with those in myelitis associated with aquaporin-4 IgG (AQP4-IgG) and myelin oligodendrocyte glycoprotein IgG (MOG-IgG).

Methods: We retrospectively reviewed data from patients with GFAP-IgG myelitis at the First Affiliated Hospital of Zhengzhou University and Henan Children's Hospital from May 2018 to May 2023.

Unveiling the mechanism of action of a novel natural dual inhibitor of SARS-CoV-2 Mpro and PLpro with molecular dynamics simulations.

In the twenty-first century, we have witnessed multiple coronavirus pandemics. Despite declining SARS-CoV-2 cases, continued research remains vital. We report the discovery of sydowiol B, a natural product, as a dual inhibitor of SARS-CoV-2 main protease (Mpro) and papain-like protease (PLpro).

Impact of civil war on the land cover in Myanmar.

Exploring the response relationship between civil war, population and land cover change is of great practical significance for social stability in Myanmar. However, the ongoing civil war in Myanmar hinders direct understanding of the situation on the ground, which in turn limits detailed study of the intricate relationship between the dynamics of the civil war and its impact on population and land. Therefore, this paper explores the response relationship between civil war conflict and population and land cover change in Myanmar from 2010 to 2020 from the perspective of remote sensing using the land cover data we produced, the open spatial demographics data, and the armed conflict location and event data project.

Predictive value of epicardial adipose tissue volume for early detection of left ventricular dysfunction in patients suspected of coronary artery disease.

Aim: To investigate the relationship between epicardial adipose tissue (EAT) and myocardial strain and the severity of coronary artery disease (CAD), and to evaluate the predictive value of EAT parameters in early left ventricular (LV) diastolic dysfunction.

Materials And Methods: One hundred seventy patients with suspected CAD who underwent both coronary computed tomography angiography and echocardiography were enrolled in 2020. LV global strains were calculated using commercial software.

Uncovering the multi-fencing effects: Changes in plant diversity across dimensions and spatio, and the relationship between diversity and stability.

Plant diversity is fundamental to maintaining grassland ecosystem function. Rangeland managers use fencing as a strategy to enhance plant diversity in degraded grasslands. However, the effects of this natural management approach on grasslands across a wide range of environmental gradients and its spatial pattern remain unclear.