Longer term follow-up of abdominal symptoms (CFAbd-Score) after initiation of Elexacaftor / Tezacaftor / Ivacaftor in adults with cystic fibrosis.

Background: Whether improvements in gastrointestinal (GI) symptoms observed with Elexacaftor/Tezacaftor/Ivacaftor (ETI) treatment are sustained in the longer-term requires exploration. This study investigated how GI-symptoms change with longer-term ETI use in pancreatic insufficient adults with cystic fibrosis (awCF).

Methods: Participants completed up to three abdominal symptom questionnaires, employing the validated CFAbd-Score.

A Pilot Study of Clinical Measures to Assess Mind-Body Intervention Effects for those with and without PTSD.

Objective: Assess measures for future mind-body interventions in those with and without PTSD.

Methods: Psychological and immune measures were assessed at baseline in three age and gender-matched groups: 1) 15 combat veterans with PTSD, 2) 15 combat veterans without PTSD, and 3) 15 non-combat veterans without PTSD. Physiological measures were assessed at baseline, during relaxation and stress conditions.

Is laparoscopic inguinal hernia repair more effective than open repair?

Objective: To systematically review randomized controlled trials, (RCT) evidence comparing Lichtenstein to total extraperitoneal (TEP) hernia repair in terms of clinical and cost effectiveness.

Study Design: Case series.

Place And Duration Of Study: The study was conducted at University of Abderdeen, U.

A prospective multicentre study of mycophenolate mofetil combined with prednisolone as induction therapy in 213 patients with active lupus nephritis.

Mycophenolate mofetil (MMF) with prednisolone has been associated with high remission rates when used as induction treatment for lupus nephritis. This prospective, multicentre, cohort study investigates the efficacy and safety of this regimen over 24 weeks in 213 Chinese patients with active lupus nephritis (Classes III, IV, V or combination). Baseline activity index (AI) was 6.