Publications by authors named "W Ghanem"
Article Synopsis
- Head and neck squamous cell carcinoma (HNSCC) shows significant genetic diversity within tumors, complicating targeted treatment approaches and making traditional imaging ineffective for detecting minimal residual disease (MRD).
- A study of 41 patients with resectable HNSCC found that circulating tumor DNA (ctDNA) can serve as a biomarker for assessing tumor heterogeneity and MRD, with notable detection rates at surgery and recurrence.
- The presence of ctDNA shortly after surgery correlated with disease recurrence, providing an early warning about potential relapse, thus supporting its role in post-operative monitoring and precision medicine strategies.
The present case series aimed to assess non-surgical elongation of the columella and reduction of cleft gaps in patients with bilateral cleft lip and palate using the active nasoalveolar molding (ANAM) device and tissue expansion principles. The study included six complete bilateral cleft patients aged one month: three males and three females. A nasoalveolar molding technique was applied using an active device (ANAM) with a 3D screw, worn by infants for two months.
View Article and Find Full Text PDFSquamous cell carcinomas of the oral cavity in young adults represent a heterogeneous entity. New prognostic biomarkers are described in the literature. The aim of this review was to identify emerging biomarkers and prognostic stratification factors of young population.
View Article and Find Full Text PDFObjectives: To describe a large cohort of eyelid and periorbital SCCs, to compare the location of the tumor and of the pathological lymph nodes, and to analyze the risk factors for lymph node involvement among tumor characteristics.
Methods: All patients managed inside our institution for an eyelid and periorbital SCCs were included. Tumor characteristics, imaging setup, excision margins, lymph node evolution features, local, regional, and distant recurrences rates, and global survival were reported.
"Ice cream cone" design of forearm free flap for orbital exenteration reconstruction.
J Plast Reconstr Aesthet Surg
August 2024
Backgrounds: Reconstruction post-orbital exenteration serves the dual purpose of expediting healing, laying the groundwork for cosmetic restoration, and minimising complications such as orbitosinusal fistulae. The aim of this study was to introduce a modified "Ice cream cone" (ICC) design of the Radial Forearm Free Flap (RFFF) technique used for reconstruction of orbital exenteration cavity, along with the oncological, functional, and aesthetic outcomes.
Methods: The authors conducted a retrospective study between January 2005 and December 2020.