Publications by authors named "W Garrett Matthews"

Article Synopsis
  • The study aims to assess how the size of the primary tumor in T3 N0-3M0 supraglottic cancers affects overall survival (OS) and disease-free survival (DFS) for patients treated with intensity-modulated radiotherapy (IMRT).
  • This retrospective cohort analysis involved 239 patients from Canadian cancer centers, measuring tumor volume via imaging and employing survival analysis methods.
  • Results indicate that larger primary tumor volume correlates with worse OS and DFS, suggesting that patients with significant tumor sizes might benefit more from surgical intervention like laryngectomy followed by radiotherapy.*
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In this Letter, an SiPM with a dedicated cooling system suitable for receiving ultra-low-power solar-blind wavelengths is reported. This is designed to decrease the temperature of the detector from 21°C to -10°C, and the corresponding dark count rate (DCR) is reduced by approximately 10 dB. A 275 nm optical wireless communication (OWC) system is established using on-off-keying (OOK) modulation.

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Silicon photomultipliers' relatively large areas and ability to detect single photons make them attractive as receivers for optical wireless communications. In this paper, the relative importance of the non-linearity and width of SiPMs' fast output in their performance in receivers is investigated using Monte Carlo simulations. Using these results, the performances of receivers containing different SiPMs are estimated.

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Importance: The association of primary tumor volume with outcomes in T3 glottic cancers treated with radiotherapy with concurrent chemotherapy remains unclear, with some evidence suggesting worse locoregional control in larger tumors.

Objective: To evaluate the association of primary tumor volume with oncologic outcomes in patients with T3 N0-N3 M0 glottic cancer treated with primary (chemo)radiotherapy in a large multi-institutional study.

Design, Setting, And Participants: This multi-institutional retrospective cohort study involved 7 Canadian cancer centers from 2002 to 2018.

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