Publications by authors named "W Gaertner"
Article Synopsis
- National guidelines recommend segmental colectomy for appendiceal neuroendocrine neoplasms larger than 2.0 cm due to risks of lymph node involvement, with conditional overall survival becoming an important prognostic tool.
- A study of 3,541 patients revealed that 16% had positive lymph nodes, and factors like size, depth of invasion, and lymphovascular involvement were correlated with metastasis.
- The findings suggest that more clinicopathologic factors should influence decisions on surgical treatment and surveillance for better survival rates, especially for patients with more aggressive histologies.
De novo or viral reactivation cancers are a major cause of morbidity and mortality in the solid organ transplant (SOT) population. Primary sclerosing cholangitis (PSC) is an aggressive disease which can lead to cholestatic liver damage and cirrhosis. PSC often cooccurs with inflammatory bowel disease (IBD).
View Article and Find Full Text PDFAim: The optimal extent of resection for splenic flexure adenocarcinoma remains debated. These tumours straddle the left- and right-sided vasculature with lymphatic drainage in a watershed area; current guidelines recommend either segmental or extended colectomy. We analysed surgical management of splenic flexure tumours and compared outcomes between approaches.
View Article and Find Full Text PDFFollowing bowel surgery, infectious complications, including anastomotic leak (AL), remain major sources of morbidity and mortality. Bowel preparation is often administered with the assumption that gut decontamination reduces post-surgical complications. In this study, we tested this hypothesis using a murine model of colon surgery.
View Article and Find Full Text PDFObjective: To investigate the long-term outcomes of patients with combined primary sclerosing cholangitis/inflammatory bowel disease (PSC-IBD) undergoing both liver transplantation (LT) and total abdominal colectomy (TAC).
Summary Background Data: The fraction of patients with PSC-IBD that require both LT and TAC is small, thereby limiting significant conclusions regarding long-term outcomes.
Methods: Adult and pediatric patients from nine centers from the US IBD Surgery Collaborative who underwent staged LT and TAC for PSC-IBD were included.