[Fatal child neglect in East Germany 1 January 1985 to 2 October 1990. Results of a multicenter study].

Unlabelled: No reliable data are available on cases of lethal child neglect in the area of the former German Democratic Republic. In a multicenter study we therefore examined the police and court records for such cases occurring in the period 1 January 1985 to 2 October 1990 in the entire area of the former German Democratic Republic.

Results: A total of 9 cases were reported to the study center.

[Lethal child abuse (through the use of physical force) in the German Democratic Republic during the period 1 January 1985 to 2 October 1990. Results of a multicenter study].

Unlabelled: No reliable data are available on cases of lethal child abuse (by active force) in the area of the former German Democratic Republic. In a multicenter study we therefore examined the police and court records for such cases occurring in the period 1 January 1985 to 2 October 1990 in the entire area of the former German Democratic Republic.

Results: The study center received information on 39 cases of lethal child abuse which correspond to approximately 7 cases per year.

Protective effects of doxycycline in mesenteric ischemia and reperfusion.

In rats splanchnic artery occlusion (SAO) of the celiac and superior mesenteric arteries for 1 hr., followed by a period of reperfusion initiates a severe form of circulatory shock, which typically leads to death within 2 hrs, characterized by multiorgan failure in which neutrophils play a central role. Doxycycline (Dc) pretreatment (10mg/kg; 2 hrs.

Reduction of central nervous system reperfusion injury in rabbits using doxycycline treatment.

Background And Purpose: Activated leukocytes appear to potentiate central nervous system reperfusion injury, and agents that block leukocyte adhesion have shown neuroprotective efficacy in experimental models. Doxycycline, a tetracycline antibiotic, inhibits leukocyte function in vitro, presumably through divalent cation binding. We used a model of focal central nervous system reperfusion injury to determine the efficacy of doxycycline treatment in preserving neurological function.