Publications by authors named "W G Van Alstine"

Hemorrhage is the second leading cause of death in patients under 46 years of age in the United States. Cessation of hemorrhage prevents hemorrhagic shock and tissue hypoxia. Controlling the bleed via direct pressure or tourniquet is often the first line of defense, but long-term care requires staples, hemostatic agents, or sealants that seal the vessel and restore blood flow.

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Article Synopsis
  • - Current treatments for diverticular disease can't stop future issues like diverticulitis or bleeding, highlighting the need for new methods to manage the condition.
  • - Researchers introduced a novel adhesive patch to mechanically support the affected colon, testing its effectiveness in a pig model to evaluate safety and performance.
  • - After 3 months, results showed that the patch significantly reduced pouch deformation and improved collagen levels in the colon tissue, suggesting it could help prevent complications associated with diverticulosis.
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Purpose: To compare nylon fibered (F) with nonfibered (NF) coils for embolization in an ovine venous model.

Materials And Methods: Four- to 8-mm-diameter, 0.035-inch F and NF coils were deployed in 24 veins in 6 sheep.

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A 6-year-old, intact male, brindled, 30-Lb English Bulldog presented to the Purdue University Veterinary Teaching Hospital with a recurrent history of hematuria, periuria, and lethargy that responded temporarily to antibiotic therapy. The work-up included a complete blood count, serum biochemical profile, complete urinalysis, diagnostic imaging (abdominal radiographs and ultrasound with contrast urography), and exploratory laparotomy. The diagnostic imaging findings and subsequent exploratory revealed a unilateral, intraluminal, right-sided, 3-cm ureteral mass extending from the proximal ureter into the renal pelvis.

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The pathophysiology of colonic diverticulosis has not been completely understood. The development of appropriate animal models is essential to study diverticular disease. To date, no large animal models are available for this disease condition.

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