Publications by authors named "W G Underwood"
Cultivated sunflower (Helianthus annuus L.) is a globally important oilseed crop that is grown primarily in the Northern Great Plains region of the United States. In September 2018, sunflower stems exhibiting brown stem lesions centered on the leaf axils and accompanied by pith degradation, consistent with symptoms of Phomopsis stem canker (PSC) disease, were sampled from a commercial field of approximately 520 hectares in Polk County, MN (47°50'24" N, 96.
View Article and Find Full Text PDFWe developed and evaluated the Digital Platform for Exercise (DPEx): a decentralized, patient-centric approach designed to enhance all aspects of clinical investigation of exercise therapy. DPEx integrated provision of a treadmill with telemedicine and remote biospecimen collection permitting all study procedures to be conducted in patient's homes. Linked health biodevices enabled high-resolution monitoring of lifestyle and physiological response.
View Article and Find Full Text PDFPretreatment prognostication, on-treatment monitoring, and early detection of physiological symptoms are considerable challenges in cancer. We describe the feasibility of high-resolution wearable data (steps per day, walking speed) to longitudinally profile physiological trajectories extracted from Apple Health data in three patients with lung cancer from diagnosis through cancer treatment after obtaining informed consent. We used descriptive statistics to describe our approach of building longitudinal physiological profiles.
View Article and Find Full Text PDFImportance: Observational data have shown that postdiagnosis exercise is associated with reduced risk of prostate cancer death. The feasibility and tumor biological activity of exercise therapy is not known.
Objective: To identify recommended phase 2 dose of exercise therapy for patients with prostate cancer.
Article Synopsis
- The study investigates how exercise impacts chemotherapy-induced peripheral neuropathy (CIPN) symptoms in breast cancer survivors, finding that exercise may activate neuromuscular function and reduce these debilitating side effects.
- Out of 5,444 breast cancer survivors surveyed, CIPN prevalence was 34%, with lower rates (28%) among those who exercised according to national guidelines compared to non-exercisers (38%).
- The results indicate that increased exercise levels are associated with a decreased prevalence of CIPN symptoms, suggesting a dose-dependent benefit of physical activity post-chemotherapy.