Cystoscopic fluorescence detector for photodetection of bladder carcinoma with hematoporphyrin derivative.

Hematoporphyrin derivative, a fluorogenic substance, tends to accumulate at higher levels in most tumor tissues after intravenous injection. These properties provide a potential application for the detection of malignant tumors. We report the development and in vitro evaluation of an instrument designed to excite and detect low levels of hematoporphyrin derivative fluorescence emitted by tumor cells in the bladder after hematoporphyrin derivative administration.

An evaluation of the leading patent equivalents services.

Patent equivalent services are useful tools for identifying patent families. A patent family consists of a group of patents in various countries which cover the same invention. The patent equivalents services provided by the three leading suppliers--Chemical Abstracts Service, Derwent Publications Ltd.

Interpretation of roentgenograms via interactive television.

The diagnostic quality of roentgenographic images transmitted by interactive television was evaluated. A series of 100 kidney, ureter and bladder, chest, and bone radiographs were read individually by five radiologists, both on direct viewing and on viewing a monitor image of the television signal. The latter was transmitted by microwave a distance of 28 miles, including four transmission legs.

Hearing and para-airport children.

Audiometric screening was carried out on 3,322 elementary and high school students living in the vicinity of Logan International Airport, Boston, in an effort to determine whether noise from aircraft had any measurable effect on their hearing. Followup examinations and additional data on children failing the screening examination made it possible to classify the hearing losses as conductive, sensorineural, or mixed. The incidence of bilateral sensorineural or mixed hearing loss in the group living directly under flight paths or immediately adjacent to runways was not significantly different from the overall average.

Remote interpretation of chest roentgenograms.

A series of 98 chest films was interpreted by two physicians on the basis of monitor display of the transmitted television signal representing the roentgenographic image. The transmission path was 14 miles long, and included one active repeater station. Receiver operating characteristic curves were drawn to compare interpretations rendered on television view of the image with classic, direct view interpretations of the same films.