Publications by authors named "W Faltyn"
Ifosfamide (IFO) is a nitrogen derivative used at different doses, alone or in combination, in the treatment of various types of solid and hematologic cancers. It is a pro-drug activated by cytochrome P450 enzymatic system into ifosforamide mustard, the alkylating component that carries out the cytotoxic effect of the IFO. The most common toxicities of IFO are gastrointestinal, cutaneous, hematological, urological, and neurological.
View Article and Find Full Text PDFAlthough patient narratives have been increasingly introduced in various fields of medicine, a standard method in clinical practice is still lacking. The objectives of this pilot study were to evaluate the feasibility and usefulness of a digital narrative diary integrated into the care pathway of patients with bone sarcoma and limb soft tissue sarcoma both from the patients' and the healthcare professionals' (HCPs) perspectives. A digital platform, DNMLAB, was designed to obtain guided narratives from patients during their pathway of care in compliance with confidentiality and data protection laws.
View Article and Find Full Text PDFArticle Synopsis
- The study examines the psychological effects of the COVID-19 pandemic on cancer patients, specifically those with sarcoma, by comparing emotional distress and quality of life between patients diagnosed during the pandemic and the previous year.
- It enrolled 114 patients, revealing that while most quality of life aspects were similar, the financial concerns and emotional distress levels were significantly worse in the COVID group, with 69.0% experiencing distress compared to 48.6% in the control group.
- The findings highlight that patients diagnosed during the pandemic felt greater anxiety about their health and perceived a decline in the quality of their care, suggesting a need for targeted psychological support during such crises.
The impact of the COVID-19 pandemic on diagnosis and treatment of patients with soft tissue and bone sarcomas or aggressive benign musculoskeletal diseases: A single-center retrospective study (SarCorD study).
Front Oncol
September 2022
Background: The COVID-19 pandemic led to a rapid reorganization of healthcare activities, leading to reduced access to clinics, interruption of screenings, and treatment schedule modifications in several cancer types. Few data are available on sarcomas. We analyzed COVID-19-related diagnostic delay in a sarcoma referral center in Italy.
View Article and Find Full Text PDFBackground: Guidelines for the implementation of narrative medicine in clinical practice exist; however, in Italy, no standard methodology is currently available for the management of oncological patients. Since 2017, at the "Regina Elena" National Cancer Institute, studies using "digital narrative diaries" (DNMLAB platform) have been carried out; this article focuses on a pilot, uncontrolled, real-life study aiming to evaluate the utility of DNM integrated with the care pathway of patients with bone and limb soft tissue sarcomas.
Methods: Adult patients completed the diary during treatment or follow-up by writing their narrative guided by a set of narrative prompts.