Publications by authors named "W F Lems"
Background: There is considerable practice variation in labelling, diagnosis and treatment of adults with sterile bone inflammation. We developed a expert consensus recommendations on the disease definition, diagnosis and treatment of this rare condition.
Methods: Systematic literature review and Grading of Recommendations, Assessment, Development and Evaluations-based appraisal of evidence, two Delphi surveys and three digital and in-person consensus meetings with a multidisciplinary expert panel and patient representatives.
Article Synopsis
- - The report by the European Calcified Tissue Society (ECTS) outlines evidence-based recommendations for preventing and treating glucocorticoid-induced osteoporosis (GIOP) in adults, aimed at healthcare providers who may not specialize in bone health.
- - Experts reviewed the literature and created 25 recommendations that categorize patients based on their fracture risk: medium, high, and very high, considering factors like age and history of fractures for appropriate treatment strategy.
- - Key general measures include optimizing calcium and vitamin D intake, assessing fracture risk regularly for those on glucocorticoids for three months or longer, and minimizing fall risks among patients.
Updated practice guideline for dual-energy X-ray absorptiometry (DXA).
Eur J Nucl Med Mol Imaging
January 2025
Article Synopsis
- The introduction of dual-energy X-ray absorptiometry (DXA) in the 1980s transformed how osteoporosis is diagnosed and managed globally.
- DXA results can be impacted by various technical factors, including instrument quality, patient positioning, and the interpretation of T-scores and Z-scores.
- This report aims to highlight important technical and clinical elements of DXA use and discusses how to better integrate these practices into clinical settings, along with considering non-bone mineral density measurements.