Publications by authors named "W F Hoffman"
A Proposed Framework to Regulate Mental Health in Airline Pilots.
Aerosp Med Hum Perform
December 2024
The current regulatory approach to U.S. airline pilot mental health may have unintended negative consequences including healthcare avoidance and screening imprecision.
View Article and Find Full Text PDFIntroduction: Aviation safety sensitive personnel (SSP) function in highly complex environments. SSP mental health is thought to support safety, efficiency, and overall health. Research is needed to identify how to optimize and screen mental health across aviation SSP, but no consensus exists on the research priorities that need to be met.
View Article and Find Full Text PDFEarly expression of neuroinflammation in an untreated fatal case of diabetic ketoacidosis.
Arch Endocrinol Metab
November 2024
Article Synopsis
- A case study analyzes a young adult who experienced lethargy and weight loss before dying, with signs suggesting worsening metabolic health over time.
- This research is the first to examine human brain tissue from a type 1 diabetes patient experiencing diabetic ketoacidosis (DKA) before treatment, comparing it to a treated patient of similar demographics.
- Results indicate neuroinflammatory markers were lower in the untreated DKA brain; dehydration may reduce inflammation, while rehydration might increase it, highlighting potential therapeutic avenues to combat neuroinflammation and related cognitive issues.
Article Synopsis
- Traumatic brain injury (TBI) can lead to nonconvulsive seizures (NCS) and status epilepticus (NCSE) in up to 30% of severe cases, significantly impacting patient outcomes, yet these conditions are hard to diagnose at the bedside due to varying symptoms.* -
- The study explores the use of a portable rapid response EEG (rr-EEG) as a diagnostic tool for NCS and NCSE, which has shown effectiveness in hospital settings but needs evaluation in pre-hospital scenarios.* -
- In a simulated training mission with a Critical Care Air Transport (CCAT) team, participants successfully set up and used the rr-EEG on a manikin, accurately identifying NCS