Publications by authors named "W F Bueno"

Article Synopsis
  • The text outlines the importance of archiving and sharing protein and nucleic acid structures for supporting research in life sciences.
  • It highlights the role of the Protein Data Bank in Europe (PDBe) in developing databases and web services to provide access to structural data, annotations, and visualization tools.
  • The document also discusses future directions for PDBe's services to address challenges posed by advancements in structure determination and modeling.
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Although the COVID pandemic has challenged the resilience of health services in general, this impact has been most visible in intensive care units (ICUs). This paper presents an exploratory study of how ICUs in Brazil have coped with the complexity stemming from the pandemic. Five guidelines for coping with complexity were adopted as analytical framework.

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Introduction: A single nucleotide polymorphism (SNP) in the gene encoding gamma interferon influences its production and is associated with severity of infectious diseases. This study aimed to evaluate the association of IFNγ+874T/A SNP with duration of disease, morbidity, and development of retinochoroiditis in acute toxoplasmosis.

Methods: A case-control study was conducted among 30 patients and 90 controls.

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Congenital toxoplasmosis is a potentially severe infection and its prevention is most often based on serological screening in pregnant women. Many cases could be prevented by simple precautions during pregnancy. Aiming to assess the knowledge about toxoplasmosis among professionals working in antenatal care in a high prevalent region, a questionnaire was administered to 118 obstetric nurses and physicians attending at primary care units and hospitals.

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Acute acquired toxoplasmosis is considered a self-limited mononucleosis-like disease that rarely requires treatment. We report an unusual severe case of disseminated toxoplasmosis complicated with meningitis and pneumonia in a previously 41-year-old healthy Brazilian man. Toxoplasmosis should be included in the differential diagnosis of acute febrile diseases due to the non-specific clinical symptoms and the possibility of severe outcome.

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