Publications by authors named "W F Bouwman"

Article Synopsis
  • The study employs spin-echo small-angle neutron scattering (SESANS) to examine a wide range of structures in polymer-carbon nanocomposites, effectively covering length scales from 10 nm to 16 μm.
  • The data processing incorporates a consistent method across two different SESANS instruments, producing reliable data that can be analyzed using established hierarchical models in software like SasView.
  • This technique significantly enhances the ability to gather information about bulk structures, surpassing traditional scattering methods and opening new avenues for analyzing polymer nanocomposites across various scales.
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Article Synopsis
  • The immune response plays a crucial role in diseases like cancer and autoimmune disorders, affecting disease progression and treatment outcomes.
  • A new technology called STAP-STP allows for simultaneous measurement of activity in different signaling pathways of immune cells by analyzing their mRNA.
  • This technology was used to create distinct activity profiles for various immune cell types and was applied in a clinical study on rheumatoid arthritis, highlighting its potential for diagnosing and developing treatments for immune-related diseases.
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Ulcerative colitis (UC) and Crohn's disease (CD) are two subtypes of chronic inflammatory bowel disease (IBD). Differential diagnosis remains a challenge. Anti-TNFα treatment is an important treatment for IBD, yet resistance frequently occurs and cannot be predicted.

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A novel spin echo small-angle neutron scattering (SESANS) concept based on a rotationally symmetric magnetic field geometry is introduced. The proposed method is similar to the conventional linear SESANS technique but uses longitudinal precession fields and field gradients in a radial direction, as typically found in neutron spin echo (NSE) spectrometers. Radial SESANS could thus be implemented as an add-on to NSE setups.

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