Publications by authors named "W Essayed"
Purpose: This systematic review aimed to collate and synthesize the available literature on the abscopal effect in Glioblastoma multiforme (GBM) neoplasms, focusing on the reported biochemical mechanisms driving the abscopal effect.
Methods: A systematic search was conducted in PubMed, Cochrane Database of Systematic Reviews, and Epistemonikos from inception to May 1, 2023. Studies exploring the abscopal effect in GBM were included.
Bilateral STA-MCA bypass for Moyamoya angiopathy associated with severe erythrodermic psoriasis.
J Stroke Cerebrovasc Dis
November 2024
Article Synopsis
- The study discusses a rare case of a 52-year-old woman diagnosed with both severe erythrodermic psoriasis and moyamoya angiopathy, a cerebrovascular condition that restricts blood flow in the brain.
- Traditionally, treatment for patients with these co-existing conditions has relied heavily on non-curative medical management due to surgical risks, but this case showcases successful surgical revascularization techniques.
- Post-surgery, careful management of psoriasis flares was necessary, and the combined approach ultimately prevented future stroke incidents in the patient.
Under what circumstances, is it ethical to perform tumor surgery on a brain-dead individual? The neurosurgeons at Brigham and Women's Hospital were recently faced with such a question when asked to operate on a 28-year-old man who was pronounced brain-dead secondary to a severe brain-stem injury. His advanced directives clearly documented a desire for organ donation. During his transplant work-up, cranial imaging suggested a possible cerebellar mass of unknown etiology that was concerning for metastatic disease.
View Article and Find Full Text PDFCavernous venous malformations (CavVMs) account for a spectrum of lesions with a shared pathogenesis. Their anatomical location dictates their clinical features and surgical treatment. Extradural and dura-based CavVMs were discussed in Part 1 of this review.
View Article and Find Full Text PDFCavernous-type malformations are venous lesions that occur in multiple locations throughout the body, and when present in the CNS, they have canonically been referred to as cavernomas, cavernous angiomas, and cerebral cavernous malformations. Herein all these lesions are referred to as "cavernous venous malformations" (CavVMs), which is congruent with the current International Society for the Study of Vascular Anomalies classification system. Even though histologically similar, depending on their location relative to the dura mater, these malformations can have different features.
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