Publications by authors named "W Ennis James"
Article Synopsis
- Embracing local knowledge is crucial for biodiversity conservation, but there is a lack of effective frameworks to incorporate this knowledge properly.
- Using a Wisdom of Crowds approach, the study tested whether diverse groups of individuals, with varying ages and fishing experience, provided better estimates of fishing quality compared to more uniform groups.
- The research found that targeting a diverse group of 31% of survey participants captured most unique responses; small diverse groups were as effective as larger ones in assessing ecological conditions, highlighting the importance of including varied knowledge holders in research.
Key functions of antibodies, such as viral neutralisation, depend on high-affinity binding. However, viral neutralisation poorly correlates with antigen affinity for reasons that have been unclear. Here, we use a new mechanistic model of bivalent binding to study >45 patient-isolated IgG1 antibodies interacting with SARS-CoV-2 RBD surfaces.
View Article and Find Full Text PDFThe two most clinically important members of the flavivirus genus, Zika virus (ZIKV) and dengue virus (DENV) pose a significant public health challenge. They cause a range of diseases in humans, from hemorrhagic to neurological manifestations, leading to economic and social burden worldwide. Nevertheless, there are no approved antiviral drugs to treat these infections.
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