Publications by authors named "W E Smiddy"
Background: Central serous chorioretinopathy (CSC) is marked by serous retinal detachments caused by fluid leakage from the retinal pigment epithelium, often associated with stress, psychiatric disorders and the use of corticosteroids. This study aims to investigate the clinical and systemic characteristics associated with BALAD in patients with CSC, comparing those with and without BALAD to clarify its function as a biomarker of CSC severity and improve diagnostic and treatment approaches.
Purpose: Compare the clinical characteristics, risk factors, and optical coherence tomography (OCT) findings in patients with Central Serous Chorioretinopathy (CSC) with and without Bacillary Layer Detachment (BALAD), and to identify the distinguishing features and associated conditions of CSC with BALAD.
Article Synopsis
- The study looked at 20 eyes from 14 patients who had surgery due to problems caused by two eye diseases: sickle cell retinopathy and diabetic retinopathy.
- Most of the surgeries were done because of serious issues like retinal detachments or bleeding inside the eye.
- The results showed that the surgery didn't really improve vision for most patients, and only some had successful fixes to their retinal problems.
Article Synopsis
- The study assessed the cost effectiveness of treating geographic atrophy (GA) using two different medications: intravitreal avacincaptad pegol (ACP) and pegcetacoplan (PEG).
- Cost analyses were conducted using 2022 Medicare reimbursement data, focusing on both hospital and non-hospital settings in Miami, with treatment outcomes drawn from previous clinical trials.
- Results showed that while ACP treatment had varying costs based on treatment frequency, it was generally less cost effective for extrafoveal lesions compared to PEG, with EOM (every other month) treatment being more cost effective than EM (every month) for ACP.
Faricimab in Previously Treated Eyes With Neovascular Age-Related Macular Degeneration: An Assessment of Durability and Treatment Outcomes.
Ophthalmic Surg Lasers Imaging Retina
September 2024
Background And Objective: This study evaluated the efficacy and durability of faricimab in patients with neovascular age-related macular degeneration (nAMD) who were previously treated with anti-vascular endothelial growth factor (anti-VEGF) agents.
Patients And Methods: This retrospective case series was conducted at a single tertiary center in the United States. It focused on nAMD patients who transitioned to faricimab after initial anti-VEGF therapy, with a follow-up period of at least 9 months.