Overweight, obesity, and cardiovascular disease in heterozygous familial hypercholesterolaemia: the EAS FH Studies Collaboration registry.

Background And Aims: Overweight and obesity are modifiable risk factors for atherosclerotic cardiovascular disease (ASCVD) in the general population, but their prevalence in individuals with heterozygous familial hypercholesterolaemia (HeFH) and whether they confer additional risk of ASCVD independent of LDL cholesterol (LDL-C) remains unclear.

Methods: Cross-sectional analysis was conducted in 35 540 patients with HeFH across 50 countries, in the EAS FH Studies Collaboration registry. Prevalence of World Health Organization-defined body mass index categories was investigated in adults (n = 29 265) and children/adolescents (n = 6275); and their association with prevalent ASCVD.

Determination of the upper limit of normal for serum anti-streptolysin-O titre in primary school children in Southern Nigeria; A model for other low resource settings.

The prevention and treatment of Rheumatic Heart disease is hinged on antibiotic administration in children with Group A (GAS) pharyngitis and Acute Rheumatic Fever (ARF). The Upper Limit of Normal (ULN) for serum Anti-streptolysin O titre (ASOT) has been employed as proof of antecedent GAS pharyngitis to fulfil the Jones' criteria for diagnosis of ARF. This value has not been generated among West African children.

Prevalence and Associated Factors of Congenital Heart Disease in Cleft Lip and Palate Patients at the University of Benin Teaching Hospital.

Background: The prevalence of congenital heart disease in patients with cleft lip and palate varies from place to place. There is a paucity of such studies in our region. This study aimed to determine the prevalence and risk factors for congenital heart defects (CHD) in children with oral clefts at the University of Benin Teaching Hospital.

Gender Differences in Clinical Characteristics and Lifestyle Behaviours of Overweight and Obese Adolescents.

Background: Energy intake and energy expenditure are different in boys and girls, especially during the adolescent period, a critical period for the development of obesity. However, gender-specific lifestyle behaviours that may influence the development of obesity among adolescent have not received sufficient attention.

Aim: To determine gender differences in male and female overweight/ obese adolescents concerning their clinical parameters, dietary, sedentary and physical activity lifestyle behaviours.

Clinical predictors of circulatory failure and coexisting morbidities in children seen in an emergency room in Southern Nigeria.

Background: Circulatory failure (shock) is a life-threatening emergency referring to a state of poor tissue perfusion and resultant anaerobic respiration at a cellular level. It is a common pathway for several severe pediatric morbidities.

Aim: We evaluated the clinical predictors of shock and coexisting morbidities in acutely-ill children.