Publications by authors named "W E Ridder"
Purpose: Several studies have reported that glaucoma patients have abnormal photopic negative response (PhNR) results compared to reference control subjects. The International Society for Clinical Electrophysiology of Vision (ISCEV) released an extended protocol for PhNR (I-PhNR) in 2018. The purpose of this study was to compare the I-PhNR protocol to a similar protocol modified (M-PhNR) to enhance the performance of the method in detecting glaucomatous damage.
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- Neurogenetic disorders linked to mutations in spectrin genes lead to a wide range of symptoms, from peripheral nervous system issues to complex syndromes, emphasizing their diverse impact.
- An international study identified 14 families with unexplained distal weakness due to heterozygous loss-of-function variants, collecting standardized clinical and imaging data to analyze the condition further.
- The research found that all 20 patients exhibited early childhood onset of distal weakness with varying severity, along with associated foot abnormalities and muscle changes, confirming the link between these genetic variants and a new syndrome characterized by primarily myogenic effects.
Article Synopsis
- A study was conducted to evaluate how patients' mindsets changed after consulting a hand surgeon, focusing on their perceptions of illness and treatment.
- 276 patients with hand and wrist conditions completed mindset questionnaires before and after their consultations, revealing significant improvements in illness perception and pain-related attitudes.
- Results indicated that while both surgical and nonsurgical patients benefitted, surgical patients showed greater improvement, suggesting a need for tailored strategies to enhance mindset in nonsurgical patients.
Background: Congenital myasthenic syndromes (CMS) are a group of genetic disorders characterized by impaired neuromuscular transmission. CMS typically present at a young age with fatigable muscle weakness, often with an abnormal response after repetitive nerve stimulation (RNS). Pharmacologic treatment can improve symptoms, depending on the underlying defect.
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