Publications by authors named "W E Chapman"
Background & Aims: Perianal fistulizing Crohn's disease (PCD) is a common and debilitating complication with elusive pathophysiology. We examined mucosal cells from patients with PCD and related conditions using a multi-omics approach.
Methods: We recruited patients with PCD (n = 24), CD without perianal disease (NPCD, n = 10), and idiopathic perianal fistulas (IPF, n = 29).
Article Synopsis
- Few studies have looked into how accurate and consistent firearms examiners are when comparing bullets, especially when they're damaged or from different types of ammunition.
- This research involved 49 forensic firearms examiners making over 3,000 bullet comparisons, focusing on two main scenarios: comparing bullets of unknown origins and bullets from different known firearms.
- Key findings showed that bullet quality significantly affects decision rates, with more inconclusive results from certain bullet types and discrepancies in decision rates among different firearm models and examiner participants.
Article Synopsis
- - The study investigates whether early restaging with endoscopy and MRI after induction therapy in rectal cancer patients influences the final treatment outcome.
- - Analyzed data from 107 patients showed that those with better interim responses had significantly higher chances of achieving complete final responses, highlighting a potential link between early assessment and ultimate success.
- - Limitations of the study include its retrospective nature and small sample size, which might affect the reliability of the findings, particularly regarding the implications of partial responses.
Despite a significant increase in utilization over the past decade, the number of donation after circulatory death (DCD) organs that are procured and transplanted in the United States (US) remains well below its potential. There is still room for expansion, as utilizing DCD organs to the fullest extent is currently the most viable solution to the persistent mismatch between supply and demand in transplantation. We convened a multidisciplinary transplantation summit to examine various aspects of DCD, with faculty members from around the world with clinical and academic interest in DCD donation and transplantation, including abdominal and cardiothoracic surgeons, organ procurement organization directors, hepatologists, and gastroenterologists.
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