Publications by authors named "W David Lane"
Objective: Thrombocytopenia is a common complication of hematopoietic stem-cell transplantation (HSCT), though many patients will become immune refractory to platelet transfusions over time. We built and evaluated an electronic health record (EHR)-integrated, standards-based application that enables blood-bank clinicians to match platelet inventory with patients using data previously not available at the point-of-care, like human leukocyte antigen (HLA) data for donors and recipients.
Materials And Methods: The web-based application launches as an EHR-embedded application or as a standalone application.
Article Synopsis
- Habitat partitioning allows brown and white shrimp to coexist by using estuarine habitats at different times, although they do overlap, particularly towards the end of their nursery residency.
- Laboratory experiments tested how the density and presence of each shrimp species impacted their growth and mortality rates.
- The study found that species identity influenced growth and survival, with smaller shrimp having higher mortality, indicating environmental changes could affect their populations in varying ways.
Thigh-based free flaps are a common second-line options in autologous breast reconstruction when the abdominal donor site is unavailable. While the profunda artery perforator (PAP) flap and gracilis-based flaps are most commonly utilized in this scenario, certain anatomic variations may favor alternative flap selection. One such option is the medial circumflex femoral artery perforator flap (MCFLAP).
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- * Anti-ABO antibodies naturally develop early in life, unlike other red blood cell antibodies, and are a major barrier to successful transfusions and transplants, with incomplete understanding of their formation.
- * Some research suggests that microbes with similar structures to ABO antigens might influence the creation of anti-ABO antibodies; however, their exact role and how the body defends against this mimicry via galectins need further exploration.
Article Synopsis
- Novel genome sequencing (GS) presents new chances to share results with healthy people, leading to a need for effective genetic counseling methods.
- A study with 466 participants used a genomic counseling model (GCM) that included a digital platform and webinars, showing that knowledge about genetics improved and decisional conflict (uncertainty in decision-making) decreased after the counseling.
- Most participants (86%) wanted to learn all GS findings after the counseling, indicating that the GCM effectively informed the general public and helped them feel more confident in decisions about genetic information.