Publications by authors named "W D Travis"
Article Synopsis
- The study surveyed pathologists and thoracic surgeons from the IASLC to evaluate their views on the R classification for lung cancer, with a response rate of 72% from 447 professionals.
- Findings revealed geographic differences in R classification usage, with Europe and Asia often reporting R status, while 70% of North American pathologists rarely do, and varied practices regarding who assigns R categories between regions.
- The "uncertain resection" category (R(un)) is largely unused globally, highlighting the need for more evidence and standardization in reporting surgical margins and R categories in pathology.
Introduction: With the implementation of low-dose computed tomography screening, multiple pulmonary tumor nodules are diagnosed with increasing frequency and the selection of surgical treatments versus systemic therapies has become challenging on a daily basis in clinical practice. In the presence of multiple carcinomas, especially adenocarcinomas, pathologically determined to be of pulmonary origin, the distinction between separate primary lung carcinomas (SPLCs) and intrapulmonary metastases (IPMs) is important for staging, management, and prognostication.
Methods: We systemically reviewed various means that aid in the differentiation between SPLCs and IPMs explored by histopathologic evaluation and molecular profiling, the latter includes DNA microsatellite analysis, array comparative genomic hybridization, TP53 and oncogenic driver mutation testing and, more recently, with promising effectiveness, next-generation sequencing comprising small- or large-scale multi-gene panels.
There are no published studies on pregnancy-related concerns, worries, and fears (CWFs) in primiparous and multiparous women and men in U.S. Air Force (USAF) families.
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- The study aims to understand how specific molecular changes, particularly the expression of a certain gene, influence the clinical outcomes of patients with pulmonary carcinoids, which can range from slow-growing to deadly tumors.
- Researchers analyzed RNA sequencing data from two cohorts of pulmonary carcinoid patients (totaling 193) to determine the prognostic value of this gene expression and its relationship with telomerase activity, which is linked to tumor aggressiveness.
- Results showed that high expression of the gene correlates with worse survival rates and is an independent predictor of poor clinical outcomes, suggesting that it could be a key factor in assessing the severity of pulmonary carcinoids.
Texting while walking (TWW) is a dual-task activity that young adults perform in their everyday lives. TWW has been reported to affect gait characteristics such as gait speed, stride length, and cadence. However, the influence of TWW on lower extremity gait function has not been investigated.
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