Publications by authors named "W D TUCKER"
Purpose: To report one-year real-world evidence on intraocular inflammation (IOI) adverse events (AEs) in patients undergoing faricimab therapy in a tertiary care hospital.
Methods: A retrospective review of electronic medical records was conducted for patients receiving faricimab treatment for neovascular age-related macular degeneration (nAMD) and diabetic macular edema (DME) at Moorfields Eye Hospital between September 1st, 2022, and August 31st, 2023. The primary outcome was the incidence of IOI (excluding endophthalmitis).
Donation after circulatory death (DCD) livers face increased risks of critical complications when preserved with static cold storage (SCS). Although machine perfusion (MP) may mitigate these risks, its cost and logistical complexity limit widespread application. We developed the Dynamic Organ Storage System (DOSS), which delivers oxygenated perfusate at 10°C with minimal electrical power requirement and allows real-time effluent sampling in a portable cooler.
View Article and Find Full Text PDFArticle Synopsis
- Indocyanine green angiography (ICGA) is crucial for diagnosing and tracking choroidal inflammation, particularly choroidal vasculitis, which is often missed by doctors not using this method during posterior uveitis assessments.
- The study analyzes ICGA signs of choroidal vasculitis, highlighting two main patterns: choriocapillaritis, which shows hypofluorescent areas indicating inflammation, and stromal choroidal vasculitis, characterized by leaking hyperfluorescent vessels.
- Overall, choroidal vasculitis is commonly found in patients with inflammatory choroid issues, and understanding its ICGA features can improve diagnosis and treatment outcomes.
Aims: Heart failure (HF) has a major impact on exercise tolerance that may (in part) be due to abnormalities in body and skeletal muscle composition. This systematic review and meta-analysis aims to assess how differences in whole-body and skeletal muscle composition between patients with HF and non-HF controls (CON) contribute to reduced peak oxygen uptake (VOpeak).
Methods And Results: The PubMed database was searched from 1975 to May 2024 for eligible studies.