Hypercoagulability in arterial disease.

Isolated human monocytes generate tissue factor when stimulated with endotoxin. Tissue factor generation provides a marker for activation of the monocyte and of the clotting system. Determination of the recalcification time of blood after incubation with endotoxin detects minute changes in coagulability.

Dexamethasone attenuates microvascular ischemia-reperfusion injury in the rat cremaster muscle.

We examined the effect of dexamethasone (DXM) pretreatment on microvascular transport of macromolecules in ischemia-reperfusion injury. The rat cremaster muscle was splayed, placed in a Lucite intravital chamber, and suffused with bicarbonate buffer. The clearance of fluorescein isothiocyanate-dextran 150 (FITC-Dx 150) was measured as an index of microvascular transport.

Partial versus complete arterial transection, fact versus fancy.

Traditionally, hemorrhage from the partially transected artery exceeds that from its completely divided counterpart. The clinical significance of this distinction is pertinent to the control of the hemorrhage in the field as well as in the operating room. To test the hypothesis the femoral arterial blood flow (Q) of seven anesthetized (pentobarbital, 30 mg/kg, IV) dogs, whose average weight was 19.

Intra-abdominal infection following combined spleen-colon trauma.

The reality of late overwhelming post-splenectomy sepsis in adults as well as children has led to more frequent attempts at splenic salvage following splenic trauma. Less attention has been paid to early septic postoperative complications in the splenectomized patient. Associated colon injury has been believed to be a relative contraindication to splenic conservation.