Publications by authors named "W D Roland"

Article Synopsis
  • Hemophagocytic lymphohistiocytosis (HLH) is a rare and severe immune disorder that is hard to diagnose due to its varied causes and symptoms, often requiring intense medical care.
  • HLH can either be genetic (HLH syndrome) or acquired (HLH disease), triggered by instances like infections, autoimmune diseases, or cancers; this case study presents the first known instance of HLH caused by tularemia in an older female patient.
  • The patient was initially treated for suspected malignancy but switched to antimicrobial therapy after testing positive for tularemia, leading to a lengthy recovery period but ultimately highlighting the need for quick identification of triggering infections for more effective HLH treatment.
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There are many industrial examples of low Reynolds number non-Newtonian flows through rectangular ducts in polymer processing. They occur in all types of manufacturing processes in which raw polymeric materials are converted into products, ranging from screw extrusion to shaping operations in dies and molds. In addition, they are found in numerous rheological measurement systems.

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A microtiter plate (MTP) method was developed to screen 1064 unique microorganisms-substrate fermentations for production of 68 target aroma compounds. Based on the number of hits identified by GC-MS, 50 fermentations were repeated at 50-mL scale in flasks. Comparison of GC-MS data showed that scaling up from MTP to flask did not generally result in large differences between the volatile profiles, even with a wide variety of substrates (juice, food slurry and food side-streams) and microorganisms (yeast, bacteria and fungi) used.

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The growing interest in plant protein sources, such as pulses, is driven by the necessity for sustainable food production and climate change mitigation strategies. Faba bean (.) is a promising protein crop for temperate climates, owing to its remarkable yield potential (up to 8 tonnes ha in favourable growing conditions) and high protein content (~29% dry matter basis).

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Article Synopsis
  • * In rare cases, tularemia can cause unusual symptoms, including skin rashes and skeletal issues, such as osteomyelitis and prosthetic joint infections.
  • * This report discusses a 73-year-old man who developed a rare acute left knee prosthetic joint infection due to tularemia, successfully treated with doxycycline.
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