Publications by authors named "W D Leslie"
Importance: Fragility fractures are often defined as those that occur after a certain age (eg, 40-50 years). Whether fractures occurring in early adulthood are equally associated with future fractures is unclear.
Objective: To examine whether the age at which a prior fracture occurred is associated with future fracture risk.
Objective: What are young children trying to express when they cry at night? According to Sadeh, parental beliefs about why their child is crying may play a role in the development and persistence of their child's insomnia. The aim of this study was to create a scale that specifically assesses these parental interpretations in different dimensions.
Methods: Children aged between 6 months and 3 years with either good sleep habits or behavioural insomnia were recruited.
Article Synopsis
- Vertebral compression fractures (VFs) and spinal degeneration are prevalent causes of back pain in older adults, with this study exploring their connection through longitudinal data from the Framingham Heart Study.
- The research found that individuals with existing VFs experienced a greater change in intervertebral disc height narrowing (DHN) over time, although the difference diminished after adjusting for various factors like age and body mass index.
- For facet joint osteoarthritis (FJOA), there was a slight increase in the change of symptoms among participants with VFs, particularly those with severe fractures, suggesting that VFs could contribute to worsening spine osteoarthritis.
Article Synopsis
- Trabecular bone score (TBS) is identified as a risk factor for fractures that is independent of bone mineral density (BMD).
- The study analyzed TBS measurements in individuals with lumbar spine compression fractures compared to controls with only thoracic fractures, finding that TBS and BMD were generally higher in those with lumbar fractures.
- It concluded that while lumbar fractures mildly increase TBS, the effect is significantly less than that on BMD and it minimally impacts TBS measurements taken from L1-L4, suggesting TBS should be reported without exclusions for lumbar fractures.
Importance: The Fracture Risk Assessment Tool (FRAX) is a fracture risk prediction tool for 10-year probability of major osteoporotic fracture (MOF) and hip fracture in the general population. Whether FRAX is useful in individuals with cancer is uncertain.
Objective: To determine the performance of FRAX for predicting incident fractures in individuals with cancer.