Publications by authors named "W D Eisner"
Objective: The effectiveness and optimal stimulation site of deep brain stimulation (DBS) for central poststroke pain (CPSP) remain elusive. The objective of this retrospective international multicenter study was to assess clinical as well as neuroimaging-based predictors of long-term outcomes after DBS for CPSP.
Methods: The authors analyzed patient-based clinical and neuroimaging data of previously published and unpublished cohorts from 6 international DBS centers.
Dystonia is a neurological movement disorder characterised by abnormal involuntary movements and postures, particularly affecting the head and neck. However, current clinical assessment methods for dystonia rely on simplified rating scales which lack the ability to capture the intricate spatiotemporal features of dystonic phenomena, hindering clinical management and limiting understanding of the underlying neurobiology. To address this, we developed a visual perceptive deep learning framework that utilizes standard clinical videos to comprehensively evaluate and quantify disease states and the impact of therapeutic interventions, specifically deep brain stimulation.
View Article and Find Full Text PDFBackground: Subthalamic deep brain stimulation (STN-DBS) reduces antiparkinsonian medications in Parkinson's disease (PD) compared with the preoperative state. Longitudinal and comparative studies on this effect are lacking.
Objective: To compare longitudinal trajectories of antiparkinsonian medication in STN-DBS treated patients to non-surgically treated control patients.
Article Synopsis
- Dystonia is a challenging condition with limited treatment options, but deep brain stimulation (DBS) targeting the internal pallidum shows promise for symptom relief.
- A study involving 80 patients explored optimal DBS electrode placements and identified different effective stimulation sites for cervical and generalized dystonia, linking these sites to specific brain structures.
- The findings indicate that while different neural pathways are involved in treating cervical versus generalized dystonia, both conditions share a common brain network that integrates connectivity to the cerebellum and somatomotor cortex.