Publications by authors named "W Collyer"
Laboratory automation technologies have revolutionized biomedical research. However, the availability of automation solutions at the single-cell level remains scarce, primarily owing to the inherent challenges of handling cells with such small dimensions in a precise, biocompatible manner. Here, we present a single-cell-level laboratory automation solution that configures various experiments onto standardized, microscale test-tube matrices via our precise ultrasonic liquid sample ejection technology, known as PULSE.
View Article and Find Full Text PDFArticle Synopsis
- Ring resonator (RR) devices are closed-loop waveguides used for circulating waves at specific resonant frequencies, applicable in sensor technology and optical tweezers.
- Developing a new acoustofluidic RR-based tweezing method improves the manipulation of micron-scale particles, enhancing trapping capabilities significantly due to higher resonance interactions and adjustable signal phases.
- This innovation paves the way for advancements in various fields such as biosensing, mechanobiology, lab-on-a-chip technologies, and understanding cell-cell communication.
Acoustic tweezers have gained substantial interest in biology, engineering, and materials science for their label-free, precise, contactless, and programmable manipulation of small objects. However, acoustic tweezers cannot independently manipulate multiple microparticles simultaneously. This study introduces acousto-dielectric tweezers capable of independently manipulating multiple microparticles and precise control over intercellular distances and cyclical cell pairing and separation for detailed cell-cell interaction analysis.
View Article and Find Full Text PDFPurpose: To establish the feasibility of single-surgeon laparoscopy with application of a novel endoscope-holder device and to compare this technique with traditional assistant-driven laparoscopic camera control.
Materials And Methods: Bilateral simple nephrectomies were performed in six pigs. On one side, the operating surgeon employed the "scope holder" and performed the surgery without a laparoscopic assistant.
Objectives: To evaluate the effects of renal vascular control and intrarenal cooling on the size of renal lesions attainable with a 3.4-mm cryoprobe.
Methods: Three groups of pigs underwent unilateral laparoscopic renal cryoablation with a 3.