Publications by authors named "W C Siu"

Background: Availability of new vaccines for adults has increased interest in understanding Canada's respiratory syncytial virus (RSV) burden in older adults and adults considered at high risk of severe infection.

Objective: To characterize the burden of RSV disease in Canada by joint analysis of the published literature and hospitalization data from a healthcare administrative database.

Methods: Electronic databases of published literature were searched to identify studies and systematic reviews reporting data on outpatient visits, hospitalizations, intensive care unit (ICU) admissions and deaths associated with RSV infection in adults.

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Article Synopsis
  • The objective is to help family physicians effectively discuss RSV immunizations with their patients.
  • There are three preventive options for severe RSV disease in infants: palivizumab for high-risk infants, nirsevimab for all infants, and the RSVpreF vaccine for pregnant individuals.
  • Family doctors need to understand each immunization option's specifics, including recommendations and patient considerations, to support informed choices for parents and infants.
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Background: The National Advisory Committee on Immunization (NACI) reviews the evolving evidence on influenza immunization and provides annual recommendations regarding the use of seasonal influenza vaccines. The updates the NACI recommendations from the previous year.

Objective: To summarize the 2024-2025 NACI seasonal influenza vaccine recommendations and to highlight new and updated information.

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