SARS-CoV-2 spike glycoprotein vaccine candidate NVX-CoV2373 immunogenicity in baboons and protection in mice.

The COVID-19 pandemic continues to spread throughout the world with an urgent need for a safe and protective vaccine to effectuate herd protection and control the spread of SARS-CoV-2. Here, we report the development of a SARS-CoV-2 subunit vaccine (NVX-CoV2373) from the full-length spike (S) protein that is stable in the prefusion conformation. NVX-CoV2373 S form 27.

The effect of polishing pastes on composite resin surfaces. A SEM study.

CLINICALLY, COMPOSITE RESINS can be polished to a smooth surface at the time of placement using a variety of polishing methods. Subsequently maintaining the finish on recalls needs to be evaluated. The purpose of this investigation was to compare surface textures of a small particle composite resin (average particle size 5 microns) after polishing with prophylaxis and polishing pastes.

Topographic classification of deformities of the alveolar process.

A system of nomenclature for deformities of the alveolar process is presented. Descriptive, familiar topographic terms are used (crater, trench, moat, ramp and plane), and specific criteria are given for each term. Two hundred randomly selected osseous deformities in dry skulls were classified by two examiners at independent sessions using the proposed system.