Publications by authors named "W C Groh"
During extrusion printing of pasty biomaterials, internal geometries are mainly adjusted by positioning of straightly deposited strands which does not allow realization of spatially adaptable density gradients in x-, y- and z-direction for anisotropic scaffolds or anatomically shaped constructs. Herein, an alternative concept for printing patterns based on sinusoidal curves was evaluated using a clinically approved calcium phosphate cement (CPC). Infill density in scaffolds was adjusted by varying wavelength and amplitude of a sinus curve.
View Article and Find Full Text PDFArticle Synopsis
- This document serves as a comprehensive guide for health care professionals on managing arrhythmias associated with neuromuscular disorders (NMDs), focusing on various specific conditions like Duchenne muscular dystrophy and myotonic dystrophy.
- It includes expert-recommended practices for diagnosing and treating arrhythmic complications, as well as provides insights into end-of-life care for these patients.
- The recommendations are based on extensive research, a consensus from specialists, and have undergone public and professional review to ensure effective and reliable clinical guidance.
Myotonic dystrophy is an inherited systemic disorder affecting skeletal muscle and the heart. Genetic testing for myotonic dystrophy is diagnostic and identifies those at risk for cardiac complications. The 2 major genetic forms of myotonic dystrophy, type 1 and type 2, differ in genetic etiology yet share clinical features.
View Article and Find Full Text PDFPurpose Of Review: Myotonic dystrophy type 1 (DM1) is a severe, progressive genetic disease that affects between 1 in 3,000 and 8,000 individuals globally. No evidence-based guideline exists to inform the care of these patients, and most do not have access to multidisciplinary care centers staffed by experienced professionals, creating a clinical care deficit.
Recent Findings: The Myotonic Dystrophy Foundation (MDF) recruited 66 international clinicians experienced in DM1 patient care to develop consensus-based care recommendations.