Influence of a 2nd Sphere Hydrogen-Bond Donor on the Reactivity of Non-heme Fe(II) Complexes in Alkane, Alkene and Aromatic Oxidation with H2O2.

Two iron(II) complexes of the pentadentate aminopyridine ligand L52(OH), bearing a 2nd sphere OH group in ortho position of one pyridine, were studied in the oxidation of various substrates using H2O2. While the addition of the OH group lowers the yields of alkane and aromatic oxidation, it improves the yield in alkene epoxidation. Spectroscopic analyses suggest that the pyridine-OH group stabilizes an Fe(III)OOH intermediate by hydrogen-bonding with the proximal O atom of hydroperoxo, but also eventually drives the system towards a dimeric structure, which competes with the oxidation process.

Reproductive success of inbred strain MV31 of the ctenophore in a self-sustaining inland laboratory culture system.

Ctenophores are an attractive phylogenetic lineage for studying animal evolution due to their early divergence from other metazoans. Among Ctenophora, is a model system for developmental, cellular, molecular genetic, and evolutionary studies. Until recently, many of these studies were conducted on wild-caught animals, limiting access to researchers on the coast.

Mobility of thiolates on Au(111) surfaces.

Self-assembled monolayers (SAMs), especially those based on thiol containing compounds on gold, are of both practical and fundamental interest. Thiols and thiolates can bind to gold in several ways due to the presence of holes and edges on the surfaces. The variety of binding motifs is increased by the presence of adatoms, gold atoms present on the surface, that sit between the thiolate and the surface.

Exploring Surface-Enhanced Raman Spectroscopy of Pyrazine-2-Carbonitrile for Indirect Label-Free Albumin Quantification in an Endothelium Permeability Assay.

Accurate, label-free quantification of proteins, and more specifically albumin, is essential in studies aimed at monitoring transport across biological barrier tissues . Surface-enhanced Raman scattering (SERS) can deliver the sensitivity and specificity needed for such studies at physiologically relevant conditions, however, direct detection of albumin is not typically feasible at such concentrations. Here we use a small-molecule reporter (pyrazine-2-carbonitrile, PCN) that can interact both with albumin and a SERS substrate to facilitate albumin quantification.

Examining the mental health trajectories of children and adolescents: a cross-cohort analysis.

Background: Epidemiological samples provide opportunity to understand the development of mental health trajectories to better understand whether such epidemiological data can help to plan and modify service delivery for youth mental health. Variation between countries is not well understood and thus applying evidence from other countries to national strategies limits support service policy and planning. We therefore examine developmental patterns of youth mental health across different countries using the Growing Up in Ireland (GUI) Cohorts, with comparison to existing UK longitudinal cohort data (Millennium Cohort Study, MCS; Growing up in Scotland, GUS).