Publications by authors named "W Brent Keeling"

Article Synopsis
  • - The study evaluated the midterm survival and clinical outcomes of the On-X mechanical mitral valve in a trial involving 401 patients over five years! - Results showed very high survival rates (99.7% at 1 year, 92.4% at 5 years) and significant improvements in patients' quality of life, with mostly falling into NYHA class I or II! - There were no notable differences in clinical or hemodynamic outcomes between the Standard and Conform-X valve sizes, suggesting stable performance for the On-X valve over time!
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Background: Valve preservation in acute type A aortic dissection (ATAAD) can be accomplished with root repair or replacement. Long-term valve durability with root repair has been established, but limited data exist regarding long-term durability of valve-sparing root replacement (VSRR). In this study, long-term results of VSRR were compared with root repair in ATAAD.

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Article Synopsis
  • Thoracic endovascular aortic repair (TEVAR) is an effective treatment for complicated acute type B aortic dissection (aTBAD), but questions remain regarding coverage length and its effects on aortic health.
  • A study reviewed 92 patients who underwent TEVAR, comparing standard coverage (zones 3 and 4) to extended coverage (zones 3 to 5), revealing extended TEVAR required longer coverage and led to better outcomes in terms of false lumen closure and fewer reinterventions.
  • Overall, extended TEVAR was found to be safe and reduced complications, but more long-term follow-up is needed to confirm any potential survival advantages over standard procedures.
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Purpose: To report the first interim analysis of the STRIKE-PE study, evaluating the safety and effectiveness of computer assisted vaccum thrombectomy (CAVT) for the treatment of acute pulmonary embolism (PE).

Materials And Methods: This prospective, international, multicenter study will enroll 600 adult patients with acute PE of ≤14 days and a right ventricle (RV)-to-left ventricle (LV) ratio of ≥0.9 who receive first-line endovascular treatment with CAVT using the Indigo Aspiration System (Penumbra, Alameda, California).

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Development of functional tricuspid regurgitation (TR) because of chronic mitral disease and subsequent heart failure is common. However, the effect of TR on clinical outcomes after transcatheter mitral valve replacement (TMVR) remains unclear. We aimed to evaluate the impact of baseline TR on outcomes after TMVR.

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